The Ames MPF and Ames II assays are modified versions of the Ames test using liquid culture instead of agar plates. The assays are based on the fluctuation method cited in OECD Guidline 471 but use 384-well microtiter plates and have a colorimetric read-out. The great advantage of this format is the lower amount of sample needed and much easier handling. The Ames MPF assays use TA98 and/or TA100, TA1535, TA1537. All these test strains are recommended in the current, formal test guidelines.

The Ames II assay differs from the Ames MPF assays in that it comprises TA98 and TAMix, consisting of 6 histidine mutant Salmonella tester strains, TA7001-TA7006. Each of these mutants can be reverted only by a specific transition or transversion, so that all possible base-pair changes can be detected by TAMix. The TA700x tester strains are not included among the recommended tester strains in the current, formal test guidelines.

Xenometrix offers practical training and in-house testing of the Ames MPF and Ames II assays in its facilities in Allschwil.



Reference Product Name Price
RUO
A01-210-S2-P
Ames MPF 98/100 - with S9 and Positive Controls $935.00
RUO
A10-210
Ames MPF 98/100 $3,035.00
RUO
A10-210-S2-P
Ames MPF 98/100 - with S9 and Positive Controls $3,740.00
RUO
C01-512-S2-P
Ames MPF PENTA I - with S9 & Positive Controls $2,160.00
RUO
C10-512
Ames MPF PENTA I $6,770.00
RUO
C10-512-S2-P
Ames MPF PENTA I - with S9 & Positive Controls $8,055.00
RUO
J05-210
Ames MPF 98/100 Aqua $1,750.00
RUO
PCO-0800
S9 Cofactor Kit for Ames MPF $295.00
RUO
PME-EM22
Ames MPF E.coli Exposure Medium $115.00
RUO
PME-IM31
Ames MPF E.coli Reversion Indicator Medium $295.00
RUO
PMM-EM02
Ames MPF / Ames II Salmonella Exposure Medium $115.00
RUO
PMM-GM00
Ames MPF/Ames II Growth Medium $115.00
RUO
PMM-IM10
Ames MPF/Ames II Salmonella Reversion Indicator Medium $350.00
RUO
PPC-AA01
Aminoanthracene - Positive Controls for Ames MPF, umuC (100 micrograms) $115.00
RUO
PPC-AC02
N4-Aminocytidine - Positive Control for Ames MPF, umuC $295.00
RUO
PPC-AF10
2-Aminofluorene - Positive Controls for Ames MPF, Ames II, umuC $235.00
RUO
PPC-AR05
Aminoacridine - Positive Controls for Ames MPF, umuC (1000 micrograms) $150.00
RUO
PPC-NF00
Nitrofluorene - Positive Controls for Ames MPF, umuC (20 micrograms) $150.00
RUO
PPC-NQ02
Nitroquinoline-N-oxide - Positive Controls for Ames MPF, umuC (20 micrograms) $150.00
RUO
PRS-PB01
Ames Rat Liver S9 (Lyophilized), PB/BN Induced (1 mL) $150.00